The other half of cases of thrombotic thrombocytopenia purpura develop when your immune system attacks platelet cells.
Thrombotic thrombocytopenic purpura can also develop in people: “Thrombotic” refers to blood clots and “thrombocytopenic” refers to low levels of platelets.Ībout 3 to 11 cases develop per 1 million people per year, and it seems to affect women more than twice as often as men.Īpproximately half of people have signs or symptoms of other medical conditions. Thrombotic thrombocytopenic purpura is a rare condition that occurs when you don’t have enough of the enzyme ADAMTS13, which leads to excessive blood clotting. Purpura are classified as thrombocytopenic and nonthrombocytopenic purpura depending on whether you have a low platelet count.